functionalized cm4 chip Search Results


cm4 sensor chips  (Biacore)
86
Biacore cm4 sensor chips
Cm4 Sensor Chips, supplied by Biacore, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cm4 sensor chips/product/Biacore
Average 86 stars, based on 1 article reviews
cm4 sensor chips - by Bioz Stars, 2026-05
86/100 stars
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mannosylated bovine serum albumine  (Dextra Laboratories Ltd)
90
Dextra Laboratories Ltd mannosylated bovine serum albumine
Mannosylated Bovine Serum Albumine, supplied by Dextra Laboratories Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mannosylated bovine serum albumine/product/Dextra Laboratories Ltd
Average 90 stars, based on 1 article reviews
mannosylated bovine serum albumine - by Bioz Stars, 2026-05
90/100 stars
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fcγ fragment specific antibody  (Jackson Immuno)
96
Jackson Immuno fcγ fragment specific antibody
FIGURE 3 Functional comparison of <t>1A12-derived</t> <t>IgG-scFv</t> and scFv-Fc bispecific T cell engagers. (A,B) Schematics of aglycosylated IgG-scFv and scFv-Fc bispecific constructs incorporating OKT3 scFvs. (C,D) SPR sensorgrams showing binding of the 1A12/OKT3 IgG-scFv and scFv-Fc to recombinant MSLN. Black lines represent the duplicate experimental response curves; red lines represent the modeled kinetic curves. Insets show analyte concentrations. (E) T cell-mediated cytotoxicity comparing the potency of the two bispecific formats on MSLN-expressing NOMO-1 cells, colored as indicated. Insets show construct schematics. (F) Resulting IFNγ and IL-2 production as a function of bispecific antibody concentration colored as indicated.
Fcγ Fragment Specific Antibody, supplied by Jackson Immuno, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/fcγ fragment specific antibody/product/Jackson Immuno
Average 96 stars, based on 1 article reviews
fcγ fragment specific antibody - by Bioz Stars, 2026-05
96/100 stars
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FIGURE 3 Functional comparison of 1A12-derived IgG-scFv and scFv-Fc bispecific T cell engagers. (A,B) Schematics of aglycosylated IgG-scFv and scFv-Fc bispecific constructs incorporating OKT3 scFvs. (C,D) SPR sensorgrams showing binding of the 1A12/OKT3 IgG-scFv and scFv-Fc to recombinant MSLN. Black lines represent the duplicate experimental response curves; red lines represent the modeled kinetic curves. Insets show analyte concentrations. (E) T cell-mediated cytotoxicity comparing the potency of the two bispecific formats on MSLN-expressing NOMO-1 cells, colored as indicated. Insets show construct schematics. (F) Resulting IFNγ and IL-2 production as a function of bispecific antibody concentration colored as indicated.

Journal: Frontiers in Drug Discovery

Article Title: Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics

doi: 10.3389/fddsv.2023.1216516

Figure Lengend Snippet: FIGURE 3 Functional comparison of 1A12-derived IgG-scFv and scFv-Fc bispecific T cell engagers. (A,B) Schematics of aglycosylated IgG-scFv and scFv-Fc bispecific constructs incorporating OKT3 scFvs. (C,D) SPR sensorgrams showing binding of the 1A12/OKT3 IgG-scFv and scFv-Fc to recombinant MSLN. Black lines represent the duplicate experimental response curves; red lines represent the modeled kinetic curves. Insets show analyte concentrations. (E) T cell-mediated cytotoxicity comparing the potency of the two bispecific formats on MSLN-expressing NOMO-1 cells, colored as indicated. Insets show construct schematics. (F) Resulting IFNγ and IL-2 production as a function of bispecific antibody concentration colored as indicated.

Article Snippet: Goat anti-human IgG, Fcγ fragment specific antibody (Jackson ImmunoResearch: 109005098) was amine coupled to 2 flow cells Frontiers in Drug Discovery frontiersin.org02 of a Series S CM4 chip (~2,800 RUs).

Techniques: Functional Assay, Comparison, Derivative Assay, Construct, Binding Assay, Recombinant, Expressing, Concentration Assay